Pulmonary embolism is an acute arterial occlusion of pulmonary artery branches by embolus, separated from the thrombus in the big blood circulation veins. In spite of many modern drugs for pulmonary embolism prophylaxis, the number of the patients with this pathology is increased for last decades. The high risk of pulmonary embolism is related to the following diseases: cardiac insufficiency, cardiac infarction, stroke, nephrotic syndrome, polycythemia, system red lupus. The highest risk of development of pulmonary embolism is observed after surgical interventions within 2 weeks. However, if we consider the modern treatment of this disease, we can say that medicine is able to prevent and to treat the problem. Medications have been developed to help in pulmonary arterial hypertension treatment. One of these drugs is Revatio.